• Assists with weight loss by utilizing fatty acids for energy. Fatty build up is prevented in organs such as the heart and
liver. Improved fat metabolism reduces the risk of damage in conditions like diabetes, alcohol-induced fatty liver and
cardiovascular disease. In human aging, Carnitine concentration in cells diminishes, affecting fatty acid metabolism in various
tissues
• Carnitine is biosynthesized primarily in the liver and kidneys from the amino acids Lysine and Methionine. Vitamin C is
essential to the synthesis of Carnitine
• L-Carnitine is required for the transport of long-chain fatty acids from the cytosol (intracellular fluid found inside cells)
in the mitochondria (membrane enclosed organelle) during the breakdown of lipids (or fats) for the generation of metabolic energy
(ATP)
• Generally 20 to 200mg per day is ingested per day be those on an omnivorous diet, while those on a strict vegetarian or vegan
diet may ingest as little as 1 mg per day. No advantage appears to exist in giving an oral dose greater than 2 grams per serve, since
absorption studies indicate saturation at this dose
WHAT IS ACETYL L-CARNITINE :
Acetyl L-Carnitine is an acetylated (introduces an acetyl functional group into the organic compound) form of L Carnitine. Other names
include Acetyl L-Carnitine HCL or N-Acetyl L-Carnitine. L-Carnitine is made in the liver and kidneys and requires the presence of
Vitamin C for its creation. It is a quaternary ammonium compound synthesized from the essential amino acids Lysine and Methionine and
performs some of the same functions, such as helping metabolize food into energy, transportation of fatty acids and consumption and
disposal of fat into the body.
WHAT DOES IT DO :
In human aging, Carnitine concentration in cells diminishes, affecting fatty acid metabolism in various tissues. Particularly adversely
affected are bones which require continuous reconstructive and metabolic functions of osteoblasts for the maintenance of bone mass.
The Carnitines exert a substantial antioxidant action, providing a protective effect against lipid peroxidation (oxidative degradation
of lipids) of phospholipids' membranes and against oxidative stress induced at the myocardial and endothelial cell level. Numerous
studies have supported the use of L-Carnitine for the treatment of high blood lipids, including lowered LDL, cholesterol and
triglyceride levels.
WHAT IS THE DIFFERENCE BETWEEN ACETYL L-CARNITINE AND L-CARNITINE?
Acetyl L-Carnitine has been claimed to be superior to normal L-Carnitine in terms of bioavailability. Acetyl L Carnitine is involved
in other aspects of neuronal metabolism and its molecular structure resembles the neurotransmitter acetylcholine.
REFERENCES :
1. Shen W, Liu K, Tian C, Yang L, Li X, Ren J, Racker L, Cotman CW, Liu J (2008).
"R-alpha-lipoic acid and acetyl-L-carnitine complementarily promote mitochondrial biogenesis in murine 3T3-L1 adipocytes". Diabetologia. 2008 Jan;51(1):165-174. Epub 2007 Nov 17.
2. Beal MF (2003).
"Bioenergetic approaches for neuroprotection in Parkinson's disease". Annals of Neurology Vol 53 Issue S3: pages S39–48; discussion S47–48.
3. Spagnoli A, Lucca U, Menasce G, Bandera L, Cizza G, Forloni G, Tettamanti M, Frattura L, Tiraboschi P, Comelli M et al (1991).
"Long Term Acetyl L-Carnitine treatment in Alzheimer's Disease". Neurology 1991 Nov;41(11):1726-32.
HEALTH PRECAUTIONS :
Courtesan Girls Acetyl L-Carnitine may aid weight loss when combined with a sensible diet, physical training or an exercise program.
Acetyl L-Carnitine is not a sole source of nutrition and should be consumed with a nutritious diet and adequate fluid intake.
Before consuming seek advice from a health care practitioner if you are unaware of your current health condition of have any
pre-existing medical conditions. This information is not intended to diagnose, treat, cure of prevent any disease.