I Am Legend by Richard Matheson

Robert Neville may well be the only survivor of an incuarble plague that has mutated every other man, woman and child into bloodthirsty, nocturnal creatures who are determined to destroy him. By day, he scavenges for food and supplies, desperate to find any other survivors who might be out there. But all the while the infected lurk in the shadows, watching his every move, waiting for him to make a mistake...