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MELANCHOLIA A Disorder of Movement and Mood A phenomenological and neurobiological review Edited by Gordon Parker and Dusan Hadzi-Pavlovic It has long been accepted that depressive disorders comprise a biologically based type - the so called 'endogenous' or 'melancholic' depression - and a residual set of depressive conditions resulting from personality style, developmental factors, and social stressors. The difficulty has been in distinguishing the melancholic type of depression on the basis of clinical features. In the belief that melancholia is capable of clinical definition, and that psychotic depression may also be clinically defined, the authors describe in this book the results of research studies seeking to distinguish those conditions from residual and more heterogeneous depressive disorders. They describe the development of a behavioural sign based approah, the CORE system and demonstrate its superiority to previous sympton based diagnostic systems. The CORE measure also identifies neurobiologically discrete groups among depressive disorders, and the authors suggest that the psychomotor disturbance indicates the likely pathogenesis of melancholic depression, involving the basal ganglia and connections to the frontal cortex. This is therefore a challening new account of the classification and neurobiology of depression, one that is certain to interest all clinicians involved in the evaluation or treatment of such patients. In addition to reviewing the historical and neurobiological evidence for melancholia as a neuropsychiatric disorder, it provides all the necessary details of the CORE diagnostic system, and the CORE measure itself is incorporate as an appendix.
ISBN 052147275X Postage - Happy to combine items. Up to 6 books (depending on weight) fit into a 3kg satchel which costs $9.60 to post anywhere in Australia. |
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